DNAcycP [1] predicts intrinsic DNA cyclizability score (C-score) defined in loop-seq assay [2]. For a sequence of length n>=50 bp, C-score of every 50-bp DNA fragment is predicted sequentially (Python package available at: https://github.com/jipingw/DNAcycP).
DNAcycP web server only allows to process only one sequence at a time no longer than 20K bp by specifying the input file in FASTA format (with sequence name line beginning with “>”) or pasting the sequence into the text box below (without sequence name line).
References:
[1] Li, K., Carroll, M., Vafabakhsh, R., Wang, X, and Wang, J.-P. (2021) DNAcycP: A Deep Learning Tool for DNA Cyclizability Prediction. Nucleic Acids Research, DOI: 10.1093/nar/gkac162
[2] Basu, A., Bobrovnikov, D.G., Qureshi, Z., Kayikcioglu, T., Ngo, T.T.M., Ranjan, A., Eustermann, S., Cieza, B., Morgan, M.T., Hejna, M. et al. (2021) Measuring DNA mechanics on the genome scale. Nature, 589, 462-467.